Cat. #151038
Anti-Cytochrome P450 4A2, 4A3 [Clo4]
Cat. #: 151038
Sub-type: Primary antibody
Unit size: 100 ug
Target: Cytochrome P450 4A2, 4A3, CYP4A2, CYP4A3
Class: Monoclonal
Application: ELISA ; IP ; WB
Reactivity: Rat
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Roland Wolf
Institute: University of Dundee
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Cytochrome P450 4A2, 4A3 [Clo4]
- Alternate name: Cyclin-Dependent Kinase 1; Cell Division Cycle 2, G1 To S And G2 To M; Cell Division Control Protein 2 Homolog; Cell Division Protein Kinase 1; P34 Protein Kinase; P34CDC2; CDC28A; CDC2; Cell Cycle Controller CDC2; CDKN1
- Research fields: Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology
- Clone: Clo4
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 51.5/52.0 kDa
- Strain: Balb/c
- Reactivity: Rat
- Host: Mouse
- Application: ELISA ; IP ; WB
- Description: The CYP2 family are part of the microsomal drug metabolising system that is responsible for the oxidation of many therapeutic agents as well as steroids, fatty acids and many other endogenous substances. The hepatic CYP4A enzymes are important fatty acid and prostaglandin omega-hydroxylases that are highly inducible by fibric acid hypolipidemic agents and other peroxisome proliferators. In humans, 4A1, 4A2, & 4A3 have been cloned from liver, kidney and testis and have been detected in renal, hepatic & brain microvessels.
- Immunogen: Rat liver cytochrome P450 4A2 and 4A3
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Cytochrome P450 4A2, 4A3, CYP4A2, CYP4A3
- Molecular weight: 51.5/52.0 kDa
- Target background: The CYP2 family are part of the microsomal drug metabolising system that is responsible for the oxidation of many therapeutic agents as well as steroids, fatty acids and many other endogenous substances. The hepatic CYP4A enzymes are important fatty acid and prostaglandin omega-hydroxylases that are highly inducible by fibric acid hypolipidemic agents and other peroxisome proliferators. In humans, 4A1, 4A2, & 4A3 have been cloned from liver, kidney and testis and have been detected in renal, hepatic & brain microvessels.
Applications
- Application: ELISA ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Lukaszewicz et al. 2013. Clin Sci (Lond). 124(5):333-42. PMID: 22938512.
- Introgression of Brown Norway CYP4A genes on to the Dahl salt-sensitive background restores vascular function in SS-5(BN) consomic rats.
