#153927

Anti-CYE1 [17C8]

Cat. #153927

Anti-CYE1 [17C8]

Cat. #: 153927

Sub-type: Primary antibody

Unit size: 100 ug

Target: Cyclin E

Class: Monoclonal

Application: WB ; IF

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Edward Kipreos

Institute: University of Georgia

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-CYE1 [17C8]
  • Alternate name: CYE-1
  • Research fields: Cell biology
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Host: Mouse
  • Application: WB ; IF
  • Description: Cyclin E is a member of the cyclin family of proteins, which regulates the cell cycle through its activation of cyclin-dependent kinases. Specifically, cyclin E binds and activates the S phase Cdk2. The cyclin E–Cdk2 complex promotes the G1 to S phase cell cycle transition. Overexpression of cyclin E has been implicated in carcinomas among the gastrointestinal tract, including colon or stomach cancer as well as a marker for breast cancers
  • Immunogen: Full-length recombinant CYE-1 protein

Target Details

  • Target: Cyclin E
  • Target background: Cyclin E is a member of the cyclin family of proteins, which regulates the cell cycle through its activation of cyclin-dependent kinases. Specifically, cyclin E binds and activates the S phase Cdk2. The cyclin ECdk2 complex promotes the G1 to S phase cell cycle transition. Overexpression of cyclin E has been implicated in carcinomas among the gastrointestinal tract, including colon or stomach cancer as well as a marker for breast cancers

Applications

  • Application: WB ; IF

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

References

  • Kim et al. 2007. Mol Cell Biol. 27(4):1394-406. PMID: 17145765.
  • The Caenorhabditis elegans replication licensing factor CDT-1 is targeted for degradation by the CUL-4/DDB-1 complex.