This antibody detects Xenopus Cyclin A in western blots.
| Institute |
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| Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151183 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Genetics |
| Application: | WB |
| Target: | Cyclin A1 |
| Reactivity: | Xenopus laevis |
| Clone: | XLA1-1 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | CCNA1; Cyclin A1; Testicular Tissue Protein Li 34; CT146 |
|---|---|
| Product description: | This antibody detects Xenopus Cyclin A in western blots. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | Xenopus laevis cyclin A |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs). Cyclin A1 is the embryonic cyclin that is present in Xenopus laevis eggs and can form complexes with CDK1 and CDK2. |
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| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Kobayashi et al. 1994. J Biol Chem. 269(46):29153-60. PMID: 7961881. Cyclin A and cyclin B dissociate from p34cdc2 with half-times of 4 and 15 h, respectively, regardless of the phase of the cell cycle. |
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