Cat. #151360
Anti-CR1 [To5]
Cat. #: 151360
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Complement Receptor Type 1 (CR1, CD35)
Class: Monoclonal
Application: FACS ; IHC ; IF ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Jacqueline Cordell
Institute: University of Oxford
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CR1 [To5]
- Research fields: Cancer;Immunology
- Clone: To5
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC ; IF ; WB
- Description: To5 may be used in studies of immune complex mediated glomerulopathies.
- Immunogen: C3b receptor-enriched precipitates from tonsil cell membranes
- Isotype: IgG1
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: Complement Receptor Type 1 (CR1, CD35)
- Target background: CR1 is found on many leucocytes and binds C3b and C4b.
Applications
- Application: FACS ; IHC ; IF ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Kremlitzka et al. 2013. Int Immunol. 25(1):25-33. PMID: 22962438.
- Complement receptor type 1 (CR1, CD35) is a potent inhibitor of B-cell functions in rheumatoid arthritis patients.
- Gerdes et al. 1982. Immunology. 45(4):645-53. PMID: 7068171.
- Human complement (C3b) receptors defined by a mouse monoclonal antibody.
- Fearon et al. 1980. J Exp Med. 152(1):20-30. PMID: 6967510.
- Identification of the membrane glycoprotein that is the C3b receptor of the human erythrocyte, polymorphonuclear leukocyte, B lymphocyte, and monocyte.
- Gerdes et al. 1980. Immunology. 39(1):75-84. PMID: 6991397.
- Xenoantiserum to human C3 receptors: its preparation and effect on the C3b and C3d receptors of tonsil cells and the C3b receptors of erythrocytes and neutrophils.
