Anti-CD72 [BU41]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-CD72 [BU41]
• Alternate name: CD72 Molecule; CD72 Antigen; Lyb-2; CD72b; LYB2
• Research fields: Immunology;Stem cell biology
• Clone: BU41
• Class: Monoclonal
• Conjugation: Unconjugated
• Strain: Balb/c
• Reactivity: Human ; Mouse
• Host: Mouse
• Application: ELISA ; FACS
• Description: CD72, a member of the C-type lectin superfamily, is a 45 kDa type II transmembrane glycoprotein. It is expressed from the pro-B through to the mature B cell stage but absent in terminally differentiated plasma cells. Ligation of CD72 enhances B cell growth and proliferation.
• Isotype: IgM
• Myeloma used: Sp2/0-Ag14

Target Details

• Target: CD72
• Target background: CD72, a member of the C-type lectin superfamily, is a 45 kDa type II transmembrane glycoprotein. It is expressed from the pro-B through to the mature B cell stage but absent in terminally differentiated plasma cells. Ligation of CD72 enhances B cell growth and proliferation.

Applications

• Application: ELISA ; FACS

Handling

• Format: Liquid
• Concentration: 1mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -15° C to -25° C
• Shipping conditions: Dry ice

References

• Knapp W. et al. 1989. Leukocyte Typing IV. Oxford University Press. ISBN-13: 978-0192618672
• Hollenbaugh et al. 1992. EMBO J. 11(12):4313-21. PMID: 1385114.
• The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co-stimulatory activity.
• Luo et al. 1992. J Immunol. 148(6):1630-4. PMID: 1371783.
• Ly-1 (CD5), a membrane glycoprotein of mouse T lymphocytes and a subset of B cells, is a natural ligand of the B cell surface protein Lyb-2 (CD72).