Monoclonal antibody directed against a marker of tumour metastasis.
| Institute |
|---|
| University of Oxford |
| Cat. #: | 151575 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Cell signaling and signal transduction;Immunology |
| Application: | ELISA ; FACS ; IHC ; IP ; WB |
| Target: | CD44v3-10-Fc |
| Reactivity: | Human |
| Clone: | 3G5 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | CD44 Molecule; Hematopoietic Cell E- And L-Selectin Ligand; GP9 Lymphocyte Homing/Adhesion Receptor; Chondroitin Sulfate Proteoglycan 8; Extracellular Matrix Receptor III; Heparan Sulfate Proteoglycan; Phagocytic Glycoprotein; Hyaluronate Receptor; Hermes Antigen; ECMR-III; HUTCH-I; Epican; CDW44; MDU2; MDU3; MIC4; LHR; Cell Surface Glycoprotein CD44; Phagocytic Glycoprotein I; Soluble CD44; CSPG8; HCELL; PGP-1; MC56; Pgp1 |
|---|---|
| Product description: | Monoclonal antibody directed against a marker of tumour metastasis. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Immunogen: | Human chimeric fusion protein CD44v3-10-Fc |
| Immunogen Uniprot ID: | P16070 |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | CD44 is an integral cell membrane glycoprotein that binds to hyaluronan and is involved in matrix adhesion, lymphocyte activation, and lymph node homing. CD44 is expressed on multiple cell types and is involved in multiple functions including cell-cell interactions and cell-extracellular matrix binding. The CD44 protein is expressed as a family of molecular isoforms generated from alternative RNA splicing and posttranslational modifications. This antibody recognizes an epitope encoded by exon v3 on the variant portion of human CD44. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | Store at -20° C frozen. Avoid repeated freeze / thaw cycles |
| Shipping conditions: | Dry ice |
| References: |
Yoo et al. 2016. Proc Natl Acad Sci U S A. :. PMID: 27872288. MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis. Liu et al. 2014. Asian Pac J Cancer Prev. 15(12):5049-53. PMID: 24998585. Fox et al. 1994. Cancer Res. 54(16):4539-46. PMID: 7519124. Normal human tissues, in addition to some tumors, express multiple different CD44 isoforms. |
|---|
| Cat. # | Tool Name | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 151016 | Anti-CyclinA [E72.1] |
Key Info
Anti-CyclinA [E72.1]
|
View Tool | |||||||||||||||||||
| 151023 | Anti-IL12 [1-1D5] |
Key Info
Anti-IL12 [1-1D5]
|
View Tool | |||||||||||||||||||
| 151025 | Anti-Vascular endothelium [10] |
Key Info
Anti-Vascular endothelium [10]
|
View Tool | |||||||||||||||||||
| 151036 | Anti-ICAM1 [15.2] |
Key Info
Anti-ICAM1 [15.2]
|
View Tool | |||||||||||||||||||
| 151040 | Anti-CD11 & CD18 [24] |
Key Info
Anti-CD11 & CD18 [24]
|
View Tool | |||||||||||||||||||
Please note we may take up to three days to respond to your enquiry.
CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.