Cat. #153221
Anti-CD22 [BU59]
Cat. #: 153221
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: CD22
Class: Monoclonal
Application: FACS ; IHC
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Margaret Goodall
Institute: University of Birmingham
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD22 [BU59]
- Alternate name: Cluster of differentiation-22; B cell receptor CD22 precursor;
- Research fields: Cancer;Cell biology;Cell signaling and signal transduction;Immunology;Stem cell biology
- Clone: BU59
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC
- Description: Cluster of differentiation 22 (CD22) is a sugar binding transmembrane protein belonging to the SIGLEC family of lectins, found on the surface of mature B cells and on some immature B cells. It acts as by preventing over activation of the immune system and the development of autoimmune diseases. CD22 which binds specifically to sialic acid with its N terminal immunoglobulin domain, is a member of the immunoglobulin superfamily due to the presence of Ig domains. CD22 functionÄËĂÂĂÂs as an inhibitory receptor for B cell receptor signalling and is also involved in the B cell trafficking to Peyer's patches in mice.
- Immunogen: Tonsil derrived B cells
- Isotype: IgG1
Target Details
- Target: CD22
- Target background: Cluster of differentiation 22 (CD22) is a sugar binding transmembrane protein belonging to the SIGLEC family of lectins, found on the surface of mature B cells and on some immature B cells. It acts as by preventing over activation of the immune system and the development of autoimmune diseases. CD22 which binds specifically to sialic acid with its N terminal immunoglobulin domain, is a member of the immunoglobulin superfamily due to the presence of Ig domains. CD22 function's as an inhibitory receptor for B cell receptor signalling and is also involved in the B cell trafficking to Peyer's patches in mice.
Applications
- Application: FACS ; IHC
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Leucocyte Typing V, (1995): edited by S.F. Schlossman, OUP, Oxford.
