Cat. #151255
Anti-AP2g [AP2g 6E4/4]
Cat. #: 151255
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Activating Protein 2 (AP-2) gamma
Class: Monoclonal
Application: IHC ; IP ; WB
Reactivity: Human ; Mouse
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Helen Hurst
Institute: Queen Mary University of London
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-AP2g [AP2g 6E4/4]
- Research fields: Cancer;Genetics;Tissue-specific biology
- Clone: AP2g 6E4/4
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 50 kDa
- Strain: Balb/c
- Reactivity: Human ; Mouse
- Host: Mouse
- Application: IHC ; IP ; WB
- Description: AP-2 is a family of developmentally regulated transcription factors which also play a role in breast cancer and melanoma. AP-2?ĂÂ may be important in cardiac and kidney development. The AP-2 transcription factors form the OB2 complex that has been shown to up-regulate c-erb-B2 transcription.
- Immunogen: Bacterially produced AP-2a/AP-2g fusion protein (c-terminal half of AP-2 gamma)
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
- Recommended controls: MCF7 cells
Target Details
- Target: Activating Protein 2 (AP-2) gamma
- Molecular weight: 50 kDa
- Tissue cell line specificity: MCF7 cells
- Target background: AP-2 is a family of developmentally regulated transcription factors which also play a role in breast cancer and melanoma. AP-2? may be important in cardiac and kidney development. The AP-2 transcription factors form the OB2 complex that has been shown to up-regulate c-erb-B2 transcription.
Applications
- Application: IHC ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Gee et al. 2009. J Pathol. 217(1):32-41. PMID: 18825690.
- Overexpression of TFAP2C in invasive breast cancer correlates with a poorer response to anti-hormone therapy and reduced patient survival.
- Eloranta et al. 2002. J Biol Chem. 277(34):30798-804. PMID: 12072434.
- Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo.
