Cat. #159675
Anti-ALCAM AZN-L50 (IgG2A) [AZNL50]
Cat. #: 159675
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Activated leukocyte cell adhesion molecule
Class: Monoclonal
Application: FACS ; IP ; WB ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Carl G. Figdor
Institute: Radboud University Medical Center (UMC)
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-ALCAM AZN-L50 (IgG2A) [AZNL50]
- Alternate name: CD166 antigen, MEMD
- Research fields: Cancer;Cell biology;Immunology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IP ; WB ; IP ; WB
- Description: ALCAM, or CD166, is a cell adhesion molecule that mediates heterotypic cell-cell contacts via its interaction with CD6, resulting in initiation and stabilization of T-cell-dendritic-cell interactions affecting T-cell activation. It also engages in homotypic cell-cell contacts. These ALCAM-ALCAM interactions have been implicated in the development and maintenance of tissue architecture and tumor progression.
- Immunogen: K562-ALCAM
- Immunogen uniprot id: Q13740
- Isotype: IgG2a
Target Details
- Target: Activated leukocyte cell adhesion molecule
- Target background: ALCAM, or CD166, is a cell adhesion molecule that mediates heterotypic cell-cell contacts via its interaction with CD6, resulting in initiation and stabilization of T-cell-dendritic-cell interactions affecting T-cell activation. It also engages in homotypic cell-cell contacts. These ALCAM-ALCAM interactions have been implicated in the development and maintenance of tissue architecture and tumor progression.
Applications
- Application: FACS ; IP ; WB ; IP ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
Related Tools
- Related tools: Anti-ALCAM AZN-L51 (IgG1) [AZNL51] monoclonal antibody
References
- Te Riet et al. 2007. J Cell Sci. 120(Pt 22):3965-76. PMID: 17971418.
