#156435

Anti-Pirt

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Cat. #156435

Anti-Pirt

Cat. #: 156435

Unit size: 100 ug

Availability: 10-12 weeks

Target: phosphoinositide interacting regulator of TRP (Pirt)

Class: Polyclonal

Application: IHC

Reactivity: Human

Host: Rabbit

£300.00

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Contributor

Institute: Johns Hopkins University

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Pirt
  • Research fields: Cell signaling and signal transduction
  • Class: Polyclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Rabbit
  • Application: IHC
  • Description: Transient receptor potential vanilloid 1 (TRPV1) is a molecular sensor of pain. Its channel activity can be modulated by several mechanisms. Phosphoinositide interacting regulator of TRP (Pirt), a membrane protein, expressed specifically in the peripheral nervous system (PNS), predominantly in nociceptive (pain) neurons has been described by several experiments indicating that Pirt is a key component of the TRPV1 complex and positively regulates TRPV1 activity. To further study this signaling pathway, a rabbit polyclonal anti-Pirt antibody that recognizes the Pirt protein has been developed.

Target Details

  • Target: phosphoinositide interacting regulator of TRP (Pirt)
  • Target background: Transient receptor potential vanilloid 1 (TRPV1) is a molecular sensor of pain. Its channel activity can be modulated by several mechanisms. Phosphoinositide interacting regulator of TRP (Pirt), a membrane protein, expressed specifically in the peripheral nervous system (PNS), predominantly in nociceptive (pain) neurons has been described by several experiments indicating that Pirt is a key component of the TRPV1 complex and positively regulates TRPV1 activity. To further study this signaling pathway, a rabbit polyclonal anti-Pirt antibody that recognizes the Pirt protein has been developed.

Applications

  • Application: IHC

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Dry ice

References

  • Kim et al. 2008. Cell. 133(3):475-85. PMID: 18455988.

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