Cat. #157950
Hedgehog Terminal Transferase Protein
Cat. #: 157950
Availability: Please enquire for quantities and pricing
Target: Hedgehog Terminal Transferase (HTTase)
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Binghamton University
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Tool name: Hedgehog Terminal Transferase Protein
- Alternate name: HTTase
- Research fields: Cell biology;Drug development;Genetics
- Source: The HTTase sequence is carried in a vector for transformation into a suitable host.
- Target: Hedgehog Terminal Transferase (HTTase)
- Description: HTTase is a water soluble protein that can covalently conjugate virtually any protein of interest with a variety of small molecules in less than 60 minutes. Conjugation by HTTase is residue specific and is active in physiological buffer at room temperature. This one-pot method for bi-molecular conjugation differs from existing techniques in that only the modifier substrate needs to be added to the "pot". Since the HTTase catalyst is fused to the protein substrate the need for cofactors or accessory proteins is eliminated. Only a single glycine residue, added to the protein target, is required for conjugation. Virtually traceless labeling is a key advantage of this system, which differentiates it from existing protein conjugation methods. Additional features include; two component labeling kinetics, site-specific, stoichiometric modifications and broad substrate tolerance.
Handling
- Shipping conditions: Dry Ice
Target Details
- Target: Hedgehog Terminal Transferase (HTTase)
