#156404

USP9x-deficient DLD-1 (with or without p53) cell line

Cat. #156404

USP9x-deficient DLD-1 (with or without p53) cell line

Cat. #: 156404

Sub-type: Continuous

Unit size: 1x10^6 cells / vial

Tissue: Colon

Disease: Cancer

Model: Knock-Out

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Fred Bunz

Institute: Johns Hopkins University

Tool Details
Target Details
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: USP9x-deficient DLD-1 (with or without p53) cell line
  • Tool sub type: Continuous
  • Parental cell: DLD-1
  • Tissue: Colon
  • Disease: Cancer
  • Model: Knock-Out
  • Description: This cell line presents an opportunity to study the effect of loss of apoptotic control on colorectal cancer cells. Study of deubiquitinase Ups9X could act as a leap towards understanding apoptotic regulation and potentially lead to new drug targets for cancer.In this technology, the gene USP9X is knocked out of two colorectal DLD-1 cells. The gene knockout has been performed by rAAV-mediated homologous recombination. The technology also consists of a double knockout line without USP9X and p...

Target Details

  • Target: USP9X and p53

Handling

  • Format: Frozen
  • Unit size: 1x10^6 cells / vial
  • Shipping conditions: Dry ice

References

  • Harris et al. 2012. Cancer Biol Ther. 13(13):1319-24. PMID: 22895071.