Cat. #156418
Tamoxifen-resistant MCF7 Breast Cancer cell line
Cat. #: 156418
Sub-type: Continuous
Unit size: 1x10^6 cells / vial
Availability: 10-12 weeks
Disease: Cancer
Model: Cancer Model
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Saraswati Sukumar
Institute: Johns Hopkins University
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Tamoxifen-resistant MCF7 Breast Cancer cell line
- Cancer: Breast cancer
- Cancers detailed: Breast cancer
- Research fields: Cancer;Drug development
- Tool sub type: Continuous
- Disease: Cancer
- Model: Cancer Model
- Description: MCF7 cells serve as a prototypic model system for human breast cancer and their response to secretive endocrine response modifiers (SERM) therapy. MCF7 cells, upon long term exposure to tamoxifen, acquire tam-resistance and continue to grow in the presence of tamoxifen. This provides a cell-based model , both in vitro and in vivo, for tam-resistant breast cancer, allows the testing of alternate therapies to tam-resistant breast cancer, or the high-throughput testing of drugs that might synergize with hormone based therapies.
- Cellosaurus id: CVCL_EG55
Target Details
- Target: tamoxifen resistant breast cancer
Handling
- Format: Frozen
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
References
- Wu et al. 2015. Mol Cell Proteomics. 14(11):2887-900. PMID: 26330541.
