Melan-Arf-1 cell line

Organism: Mouse

Tissue: Skin

Disease: Non-cancer

Model: Immortalised non-cancerous cell lines

£575.00

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Contributor

Inventor: Elena Sviderskaya

Institute: St. George's University London

Primary Citation: Sviderskaya EV, et al. J Natl Cancer Inst. 2002 Mar 20;94(6):446-54. PMID: 11904317

Tool Details

Applications

Handling

References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

Name: Melan-Arf-1 cell line
Research fields: Tissue-specific biology
Organism: Mouse
Gender: Unspecified
Tissue: Skin
Disease: Non-cancer
Morphology: Small, oval-fusiform
Growth properties: Adherent
Model: Immortalised non-cancerous cell lines
Crispr: No
Conditional: No
Description: The melan-Arf-1 and -2 cell lines are immortal melanocyte cell lines derived from the skin of neonatal Arf–/– C57BL/6J mice. These cells are Arf-null but p16Ink4a-competent. These cells are visibly pigmented and display morphology typical of normal melanocytes and can be useful in studying the role of Arf in melanoma progression.
Application: Melanocyte cell biology
Biosafety level: BSL1

Applications

Application: Melanocyte cell biology

Handling

Growth medium: RPMI + FBS (10%) + TPA (200 nM) + cholera toxin (CT) (200 pM)
Storage conditions: liquid N2

References

Sviderskaya EV, et al. J Natl Cancer Inst. 2002 Mar 20
94(6):446-54. PMID: 11904318