Cat. #151445
1-7HB2 Cell Line
Cat. #: 151445
Sub-type: Continuous
Unit size: 1x10^6 cells / vial
Availability: 10-12 weeks
Organism: Human
Tissue: Breast
Disease: Normal
Model: Immortalised Line
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Joyce Taylor-Papadimitriou
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: 1-7HB2 Cell Line
- Research fields: Cell biology
- Tool sub type: Continuous
- Parental cell: MTSV1-7
- Organism: Human
- Tissue: Breast
- Disease: Normal
- Growth properties: Morphology, adhesion properties
- Model: Immortalised Line
- Description: The 1-7HB2 cell line is a clonal derivative of the human mammary luminal epithelial cell line MTSV1-7 identified by screening for branching morphology. It is a potent tool for in vitro study of branching morphogenesis of human mammary epithelial cells and the role of integrins in mammary morphogenesis. MTSV1-7 is a clonal non-tumourigenic cell line developed by immortalizing luminal epithelial cells cultured from milk using the SV40 T antigen. The cell line forms branching structures in the presence of fibroblast cultures or fibroblast-conditioned medium and forms spheroids in collagen type I gels.
- Cellosaurus id: CVCL_2261
Handling
- Format: Frozen
- Growth medium: DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + Hydrocortisone (5 ??g/ml) + Bovine Insulin (10 ??g/ml).
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
Related Tools
- Related tools: 1-7 CE1 Cell Line
References
- Bartek et al. 1991. Proc Natl Acad Sci U S A. 88(9):3520-4. PMID: 1708884.
- Efficient immortalization of luminal epithelial cells from human mammary gland by introduction of simian virus 40 large tumor antigen with a recombinant retrovirus.
