Cat. #151273
Anti-XRCC2 [XRCC2 7B7/3] mAb
Cat. #: 151273
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: XRay Repair Cross Complementing 2 (XRCC2)
Class: Monoclonal
Application: WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Stephen West
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-XRCC2 [XRCC2 7B7/3] mAb
- Research fields: Genetics;Microbiology
- Clone: XRCC2 7B7/3
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 33 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: WB
- Description: X-Ray Repair Cross Complementing 2 (XRCC2) is a RAD51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. XRCC2 is also a component of the homologous recombination pathway.
- Immunogen: His-tagged human XRCC2
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
- Recommended controls: HeLa nuclear extracts.
Target Details
- Target: XRay Repair Cross Complementing 2 (XRCC2)
- Molecular weight: 33 kDa
- Tissue cell line specificity: HeLa nuclear extracts.
- Target background: X-Ray Repair Cross Complementing 2 (XRCC2) is a RAD51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. XRCC2 is also a component of the homologous recombination pathway.
Applications
- Application: WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Masson et al. 2001. Genes Dev. 15(24):3296-307. PMID: 11751635.
- Masson et al. 2001. Genes Dev. 15(24):3296-307. PMID: 11751635.
- Identification and purification of two distinct complexes containing the five RAD51 paralogs.
- Cartwright et al. 1998. Nucleic Acids Res. 26(13):3084-9. PMID: 9628903.
- The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family.
