Anti-UCP2 [A1P2A9*F5]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-UCP2 [A1P2A9*F5]
• Research fields: Cell biology;Metabolism
• Class: Monoclonal
• Conjugation: Unconjugated
• Molecular weight: 36
• Strain: Balb/c
• Reactivity: Human
• Host: Mouse
• Application: ELISA ; IHC ; WB
• Description: A monoclonal antibody against Uncoupling Protein 2 (UCP2). UCPs are members of mitochondrial anion carrier proteins (MACP) family. UCPs create proton leaks across the inner to outer mitochondrial membrane by uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. It is thought to play a role in non-shivering thermogenesis, obesity and diabetes. The main function of UCP2 is the control of mitochondria-derived reactive oxygen species.
• Immunogen: P55851
• Immunogen uniprot id: P55851
• Isotype: IgG1 kappa
• Myeloma used: P3X63Ag8.653
• Recommended controls: ELISA- Peptide immunogen, Western Blot- HEK293 engineered to overexpress UCP2 cell lysate, Mass spectrometry-peptide analysis of band (western blot), IHC- formalin-fixed, paraffin-embedded multi-tissue microarray (expression was profiled over 54 different human tissues))

Target Details

• Target: Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2)
• Molecular weight: 36
• Target background: A monoclonal antibody against Uncoupling Protein 2 (UCP2). UCPs are members of mitochondrial anion carrier proteins (MACP) family. UCPs create proton leaks across the inner to outer mitochondrial membrane by uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. It is thought to play a role in non-shivering thermogenesis, obesity and diabetes. The main function of UCP2 is the control of mitochondria-derived reactive oxygen species.

Applications

• Application: ELISA ; IHC ; WB

Handling

• Format: Liquid
• Unit size: 100 ug
• Shipping conditions: Dry ice