Cat. #151749
Anti-SPAG1 [10G1/2]
Cat. #: 151749
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: SPAG1
Class: Monoclonal
Application: IF ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Tatjana Crnogorac-Jurcevic
Institute: Queen Mary University of London
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-SPAG1 [10G1/2]
- Research fields: Cancer;Developmental biology
- Clone: 10G1/2
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 104 kDa
- Reactivity: Human
- Host: Mouse
- Application: IF ; IP ; WB
- Description: Sperm-associated antigen 1 (SPAG1) has been shown to be expressed in high levels in pancreatic adenocarcinoma. SPAG1 is found in high levels in testis and a large proportion of pancreatic ductal adenocarcinomas (PDAC). It has been seen that in PDAC's SPAG1 expression is predominantly cytoplasmic and confined to malignant cells. The extent and intensity of SPAG1 expression has been shown to be associated with stage and tumour nodal status and this has led to the suggestion that SPAG1 is a novel marker of PDAC progression.
- Immunogen: Synthetic peptide SPA-3 (sequence designed to avoid TPR motifs - KTAPFNKEKERRKIEIQEVNE)
- Isotype: IgG
- Myeloma used: Sp2/0-Ag14
- Recommended controls: testis, pancreatic adenocarcinoma
Target Details
- Target: SPAG1
- Molecular weight: 104 kDa
- Tissue cell line specificity: testis, pancreatic adenocarcinoma
- Target background: Sperm-associated antigen 1 (SPAG1) has been shown to be expressed in high levels in pancreatic adenocarcinoma. SPAG1 is found in high levels in testis and a large proportion of pancreatic ductal adenocarcinomas (PDAC). It has been seen that in PDAC's SPAG1 expression is predominantly cytoplasmic and confined to malignant cells. The extent and intensity of SPAG1 expression has been shown to be associated with stage and tumour nodal status and this has led to the suggestion that SPAG1 is a novel marker of PDAC progression.
Applications
- Application: IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Neesse et al. 2007. Oncogene. 26:1533-45. [PMID: 16983343]
