#161640

Anti- sodium/iodide symporter (NIS) [VJ1]

Cat. #161640

Anti- sodium/iodide symporter (NIS) [VJ1]

Cat. #: 161640

Sub-type: Primary antibody

Target: Human Sodium iodide symporter (NIS), epitope between amino acid 272 and 515 located within the last three extracellular loops

Class: Monoclonal

Application: FACS, IF, IHC, not WB after epitope denaturation

Reactivity: Human

Host: Mice

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Sabine Costagliola

Institute: Universite Libre de Bruxelles

Primary Citation: Costagliola et al. 2000. J Clin Endocrinol Metab. 85(7):2366-9. PMID: 10902780.

Tool Details
Target Details
Applications

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti- sodium/iodide symporter (NIS) [VJ1]
  • Cancer: Thyroid cancer
  • Research fields: Cancer
  • Clone: VJ1
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Reactivity: Human
  • Host: Mice
  • Application: FACS, IF, IHC, not WB after epitope denaturation
  • Description: VJ1 is a monoclonal antibody to human NIS that recognizes an epitope located between amino acid 272 and 515 located within the last three extracellular loops
  • Immunogen: pCDNA3-hNIS (genetic immunization)
  • Isotype: IgG1,k

Target Details

  • Target: Human Sodium iodide symporter (NIS), epitope between amino acid 272 and 515 located within the last three extracellular loops
  • Target background: Sodium iodide symporter (NIS) is a gene responsible for the transport of iodide into the thyroid gland and is located in the basolateral membrane of thyroid follicular cells. NIS is also expressed in extrathyroidal tissues, including transformed cells, and its expression may be used as a biomarker for diagnostic, prognostic, and therapeutic purposes.

Applications

  • Application: FACS, IF, IHC, not WB after epitope denaturation