#162128

Anti-Laminin alpha 5 [4B12]

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Cat. #162128

Anti-Laminin alpha 5 [4B12]

Cat. #: 162128

Target: Laminin alpha 5

Class: Monoclonal

Application: IF/ICC

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Sulev Ingerpuu

Institute: University of Tartu

Primary Citation: Pook et al. 2014. J Thromb Haemost. 12(4):519-27. PMID: 24450402

Tool Details
Target Details
Applications
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Laminin alpha 5 [4B12]
  • Clone: 4B12
  • Class: Monoclonal
  • Conjugation: Conjugated - Biotin
  • Cell signalling pathway: ERK
  • Molecular weight: 400 kDa
  • Reactivity: Human
  • Host: Mouse
  • Disease: Nephrotic Syndrome, Type 26 and Bent Bone Dysplasia Syndrome 2
  • Application: IF/ICC
  • Description: Anti-Laminin alpha 5 (LMa5) biotinylated monoclonal antibody, clone 4B12. Biotinylated antibody against LMa5 used in IHC and ICC.
  • Immunogen: Natural human laminin-511 purified from A549 lung adenocarcinoma cells
  • Isotype: IgG
  • Recommended controls: Mouse IgG is recommended as a control for IF and FC

Target Details

  • Target: Laminin alpha 5
  • Target alternate names: LAMA5, Laminin, alpha 5, laminin subunit alpha 5
  • Molecular weight: 400 kDa
  • Target background: Laminin alpha 5 is one of the subunits of laminin 5, one of the extracellular matrix glycoproteins abundantly present in the basement membranes of blood vessels. Laminin 5 is involved in many biological processes, such as cell adhesion, differentiation, migration, signalling, neurite outgrowth and metastasis.

Applications

  • Application: IF/ICC
  • Application notes: For IF on platelets, a working concentration of 3 ug/mL is recommended

Related Tools

  • Related tools: Monoclonal antibody 8G9 anti laminin alpha 5

References

  • Schmal et al. 2016. Stem Cells Int. 4148093, PMID: 26839560
  • Pook et al. 2014. J Thromb Haemost. 12(4):519-27. PMID: 24450402