![Western blot was performed using anti-sCD40 (soluble) [T8P2G4*A6] applied to Jurkat cell lysates](https://cdn-ilckdcl.nitrocdn.com/MBaePtwnBApFeVkjJnkSzqjAKXyRSkYH/assets/images/optimized/rev-205640f/cancertools.org/wp-content/uploads/1c76a8dc-a1c6-4abf-95f4-91ee101e82b9.png)
Cat. #152605
Anti-sCD40 (soluble) [T8P2G4*A6] mAb
Cat. #: 152605
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40 soluble form)
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ayham Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-sCD40 (soluble) [T8P2G4*A6] mAb
- Alternate name: CD4 Molecule; CD4L Receptor; TNFRSF5; CDW4; Bp5; Tumor Necrosis Factor Receptor Superfamily; Member; B Cell Surface Antigen CD4; CD4 Antigen; P5
- Research fields: Cancer;Cell signaling and signal transduction
- Clone: T8P2G4*A6
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 22 kDa
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: CD40 is a 48 kD type I glycoprotein and a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.
- Immunogen: Ovalbumin-conjugated synthetic peptide RDPVCHPLGA (C-terminal sequence)
- Isotype: IgG2b kappa
- Recommended controls: IHC - formalin-fixed, paraffin-embedded hepatocellular carcinoma sections; WB - Jurkat cell lysates
Target Details
- Target: CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40 soluble form)
- Molecular weight: 22 kDa
- Tissue cell line specificity: IHC - formalin-fixed, paraffin-embedded hepatocellular carcinoma sections; WB - Jurkat cell lysates
- Target background: CD40 is a 48 kD type I glycoprotein and a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
