#152605

Anti-sCD40 (soluble) [T8P2G4*A6] mAb

Cat. #152605

Anti-sCD40 (soluble) [T8P2G4*A6] mAb

Cat. #: 152605

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-5 days

Target: CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40 soluble form)

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-sCD40 (soluble) [T8P2G4*A6] mAb
  • Alternate name: CD4 Molecule; CD4L Receptor; TNFRSF5; CDW4; Bp5; Tumor Necrosis Factor Receptor Superfamily; Member; B Cell Surface Antigen CD4; CD4 Antigen; P5
  • Research fields: Cancer;Cell signaling and signal transduction
  • Clone: T8P2G4*A6
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 22 kDa
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: CD40 is a 48 kD type I glycoprotein and a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.
  • Immunogen: Ovalbumin-conjugated synthetic peptide RDPVCHPLGA (C-terminal sequence)
  • Isotype: IgG2b kappa
  • Recommended controls: IHC - formalin-fixed, paraffin-embedded hepatocellular carcinoma sections; WB - Jurkat cell lysates

Target Details

  • Target: CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40 soluble form)
  • Molecular weight: 22 kDa
  • Tissue cell line specificity: IHC - formalin-fixed, paraffin-embedded hepatocellular carcinoma sections; WB - Jurkat cell lysates
  • Target background: CD40 is a 48 kD type I glycoprotein and a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C