Cat. #151685
Anti-RACO1 [5H10]
Cat. #: 151685
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: RACO1
Class: Monoclonal
Application: ELISA ; IP ; WB
Reactivity: Human ; Mouse ; Rat
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Axel Behrens
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-RACO1 [5H10]
- Alternate name: Ring Finger Protein 187; RING Domain AP1 Coactivator 1; Protein RNF187; RACO1
- Research fields: Cell signaling and signal transduction
- Clone: 5H10
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: CD1
- Reactivity: Human ; Mouse ; Rat
- Host: Mouse
- Application: ELISA ; IP ; WB
- Description: RING-domain-containing protein (RACO-1) is a c-Jun co-activator that is regulated by the MEK signalling pathway. RACO-1 is a molecular link between growth factor signalling and AP-1. RACO-1 depletion reduces cellular proliferation and decreases expression of several growth-associated AP-1 target genes such as cdc2, cyclin D1 and hb-egf.
- Immunogen: Single C-terminal immunogenic peptide
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: RACO1
- Target background: RING-domain-containing protein (RACO-1) is a c-Jun co-activator that is regulated by the MEK signalling pathway. RACO-1 is a molecular link between growth factor signalling and AP-1. RACO-1 depletion reduces cellular proliferation and decreases expression of several growth-associated AP-1 target genes such as cdc2, cyclin D1 and hb-egf.
Applications
- Application: ELISA ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Davies et al. 2010. Nat Cell Biol. 12(10):963-72. PMID: 20852630.
- Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation.
