Anti-PLAP [HD 8B6]

Cat. #151107

Anti-PLAP [HD 8B6]

Cat. #: 151107

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Placental Alkaline Phosphatase (PLAP), Regan and Nagao isoenzymes.

Class: Monoclonal

Application: IF ; ELISA ; IHC ; RIA

Reactivity: Human

Host: Mouse


This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.


Inventor: Walter Bodmer

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details

Tool Details


  • Name: Anti-PLAP [HD 8B6]
  • Research fields: Cancer;Cell biology
  • Clone: HD 8B6
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: IF ; ELISA ; IHC ; RIA
  • Description: HD 8B6 has potential uses in the diagnosis of ovarian and testicular tumours. The antibody detects both Regan and Nagao isoenzymes.
  • Immunogen: Fresh Hep-2 cells followed by booster injections of fresh Hep-2 cells that have had their surface expression of PLAP boosted in culture.
  • Immunogen uniprot id: P05187
  • Isotype: IgG2a
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: Placental Alkaline Phosphatase (PLAP), Regan and Nagao isoenzymes.
  • Target background: Alkaline phosphatases are phosphodiesterases. The placental-specific isozyme of Alkaline Phosphatase (PLAP) is found in trophoblast cells of normal human mature placenta, seminomas of testis and ovarian carcinomas. The detection of alkaline phosphatase in serum is a marker for ovarian and testicular cancer.


  • Application: IF ; ELISA ; IHC ; RIA


  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C


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  • Monoclonal antibodies to placental alkaline phosphatase: preclinical evaluation in a human xenograft tumour model of F(ab')2 and Fab fragments.