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Cat. #151142
Anti-p53 [Pab 1103]
Cat. #: 151142
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: p53. Large T-associated form of p53
Class: Monoclonal
Application: IHC ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Lionel Crawford
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Primary Citation: Leppard et al. 1983. EMBO J. 2(9):1457-64. PMID: 11892796.
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-p53 [Pab 1103]
- Cancer: Other
- Cancers detailed: Broadly Applicable
- Research fields: Apoptosis and autophagy;Cancer;Cell biology;Genetics
- Clone: Pab 1103
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 53 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: IHC ; IP ; WB
- Description: Pab 1103 is an antibody developed against p53, Pab 1103 has an affinity for p53 associated with large T cell.
- Immunogen: A slice of gel containing p53 homogenised in PBS. The p53 was extracted from the human SV40-transformed fibroblast cell line SV80 and purified by immunoprecipitation and SDS gel electrophoresis.
- Isotype: IgM
- Recommended controls: MDA-MB-231 cell line
Target Details
- Target: p53. Large T-associated form of p53
- Molecular weight: 53 kDa
- Tissue cell line specificity: MDA-MB-231 cell line
- Target background: p53 is a stress-regulated transcription factor that regulates cell cycle arrest and was first identified as an SV40 large T antigen-binding protein. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas. Pab 1103 is an antibody developed against p53, Pab 1103 has an affinity for p53 associated with large T cell.
Applications
- Application: IHC ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Leppard et al. 1984. J Virol. 50(2):457-64. PMID: 6323746.
- Leppard et al. 1983. EMBO J. 2(9):1457-64. PMID: 11892796.
