#160638

Anti-ORF33 [ORF33]

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Cat. #160638

Anti-ORF33 [ORF33]

Cat. #: 160638

Sub-type: Primary antibody

Unit size: 100 ug

Target: Open Reading Frame 33

Class: Monoclonal

Application: WB

Reactivity: Other Species

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Fanxiu Zhu

Institute: Florida State University Research Foundation

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-ORF33 [ORF33]
  • Research fields: Genetics;Microbiology
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Other Species
  • Host: Mouse
  • Application: WB
  • Description: Kaposi's sarcoma-associated herpesvirus (KSHV) has been identified as the causative agent of Kaposi's sarcoma, the most common malignancy in HIV-infected individuals. KSHV has also been shown to be be associated with two lymphoproliferative diseases (Fu et al., 2015). This mouse monoclonal antibody for KSHV (tegument) protein open reading frame 33 (ORF 33) was generated using a bacterially produced recombinant protein as an antigen. ORF33 has been shown to be a crucial component of progeny virion production in conjunction with ORF45. ORF33 binding domain has been mapped to the highly conserved carboxyl-terminal 19 aa of ORF 45 and to USP7 binding domain according to Gillen et al., 2015. ORF33 has also been shown to interact with ORF38.
  • Immunogen: A bacterially produced recombinant ORF 33 protein was used as an antigen
  • Isotype: IgG

Target Details

  • Target: Open Reading Frame 33
  • Target background: Kaposi's sarcoma-associated herpesvirus (KSHV) has been identified as the causative agent of Kaposi's sarcoma, the most common malignancy in HIV-infected individuals. KSHV has also been shown to be be associated with two lymphoproliferative diseases (Fu et al., 2015). This mouse monoclonal antibody for KSHV (tegument) protein open reading frame 33 (ORF 33) was generated using a bacterially produced recombinant protein as an antigen. ORF33 has been shown to be a crucial component of progeny virion production in conjunction with ORF45. ORF33 binding domain has been mapped to the highly conserved carboxyl-terminal 19 aa of ORF 45 and to USP7 binding domain according to Gillen et al., 2015. ORF33 has also been shown to interact with ORF38.

Applications

  • Application: WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

References

  • Wu et al. 2016. J Virol. 90(4):1741-56. PMID: 26637455.
  • Gillen et al. 2015. J Virol. 89(9):4918-31. PMID: 25694600.