Cat. #152664
Anti-NS5B [1A4]
Cat. #: 152664
Unit size: 100 ug
Target: Hepatitis C virus non-structural protein 5B
Class: Monoclonal
Application: IF ; WB
Reactivity: Virus
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: A*STAR Accelerate Technologies Pte Ltd
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-NS5B [1A4]
- Research fields: Microbiology
- Clone: 1A4
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Virus
- Host: Mouse
- Application: IF ; WB
- Description: Hepatitis C virus (HCV) encodes a polyprotein that is cleaved into at least 10 viral proteins namely E1, E2, core, p7, NS2, NS3, NS4A, NS4B, NS5A, and NS5B. Non-structural 5B protein (NS5B) is HCVÄËĂÂĂÂs RNA dependant RNA polymerase and is critical for viral replication.
- Immunogen: GST-NS5B (residues 1-346) fusion protein of a HCV genotype 2a strain
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Hepatitis C virus non-structural protein 5B
- Target background: Hepatitis C virus (HCV) encodes a polyprotein that is cleaved into at least 10 viral proteins namely E1, E2, core, p7, NS2, NS3, NS4A, NS4B, NS5A, and NS5B. Non-structural 5B protein (NS5B) is HCVÄËĂÂĂÂs RNA dependant RNA polymerase and is critical for viral replication.
Applications
- Application: IF ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Aweya et al. 2015. Virology. 474:41-51. PMID: 25463603.
- NS5B induces up-regulation of the BH3-only protein, BIK, essential for the hepatitis C virus RNA replication and viral release.
