The matrix 1 (M1) protein of the influenza A virus forms a coat inside the viral envelope and is the most abundant protein in virions. The M1 protein of influenza A virus has multiple regulatory functions during the infectious cycle and these include mediation of nuclear export of viral ribonucleoproteins, inhibition of viral transcription and […]
| Institute |
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| A*STAR Accelerate Technologies Pte Ltd |
| Cat. #: | 152662 |
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| Unit size: | 100 ug |
| Research Fields: | Microbiology |
| Application: | ELISA ; IF ; Fn ; WB |
| Target: | Influenza A virus matrix 1 protein |
| Reactivity: | Virus |
| Clone: | 1G1A12 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | The matrix 1 (M1) protein of the influenza A virus forms a coat inside the viral envelope and is the most abundant protein in virions. The M1 protein of influenza A virus has multiple regulatory functions during the infectious cycle and these include mediation of nuclear export of viral ribonucleoproteins, inhibition of viral transcription and a crucial role in virus assembly and budding. |
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| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Immunogen: | GST-M1 fusion protein |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | The matrix 1 (M1) protein of the influenza A virus forms a coat inside the viral envelope and is the most abundant protein in virions. The M1 protein of influenza A virus has multiple regulatory functions during the infectious cycle and these include mediation of nuclear export of viral ribonucleoproteins, inhibition of viral transcription and a crucial role in virus assembly and budding. |
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| Format: | Liquid |
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| Concentration: | 1mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Barnwal et al. 2015. Antiviral Res. 116:55-61. PMID: 25666762. A monoclonal antibody binds to threonine 49 in the non-structural 1 protein of influenza A virus and interferes with its ability to modulate viral replication. |
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