Glycoprotein IIb/IIIa, also known as integrin a2b3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrinogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann’s thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.
| Institute |
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| Versiti Blood Research Institute |
| Cat. #: | 153807 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Immunology |
| Target: | Integrin Alpha 4b (GPIV, CD36) |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | CD-36 |
|---|---|
| Product description: | Glycoprotein IIb/IIIa, also known as integrin a2b3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrinogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Target background: | Glycoprotein IIb/IIIa, also known as integrin aIIb?ĂÂ3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder. |
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| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -20° C |
| Shipping conditions: | Dry ice |
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