Anti-IGF

Insulin-like growth factor 1 (IGF-1) is produced by the liver and skeletal muscle as well as many other tissues in response to growth hormone (GH) stimulation. IGF-1 mediates many of the actions of GH, stimulating the growth of bones and other tissues and promoting the production of lean muscle mass. IGF-1 is a useful indicator […]

Contributors

Inventor Institute
Abdo Alnabulsi Vertebrate Antibodies Limited
Cat. #: 158051
Unit size: 100 ug
Research Fields: Cell biology;Immunology
Application: ELISA
Target: Insulin-like growth factor 1 (IGF)
Reactivity: Avian
Host: Rabbit
Class: Polyclonal
Product description: Insulin-like growth factor 1 (IGF-1) is produced by the liver and skeletal muscle as well as many other tissues in response to growth hormone (GH) stimulation. IGF-1 mediates many of the actions of GH, stimulating the growth of bones and other tissues and promoting the production of lean muscle mass. IGF-1 is a useful indicator of average GH levels. The IGF-1 test is therefore often used to help evaluate for GH deficiency or GH excess. IGF-1 deficiencies are seen early in life and are usually the result of GH deficiency. They can inhibit bone growth and overall development and can result in a child with a shorter than normal stature. In adults, decreased production can lead to low bone density, less muscle mass, and altered lipid levels. Insulin-like growth factor 1 (IGF-1) is an evolutionary conserved peptide, which has been shown to be essential in the regulation of body size, the pattern of reproductive investment and life span across a broad taxonomic range of model species in laboratory and domesticated conditions. However, studies addressing corresponding evolutionary hypotheses on a broader scale and in free-living vertebrates are very rare. This is a very useful research tool to monitor muscle development and metabolism in birds.
Conjugation: Unconjugated
Molecular weight: 17
Immunogen: Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved in all bird species
Target background: Insulin-like growth factor 1 (IGF-1) is produced by the liver and skeletal muscle as well as many other tissues in response to growth hormone (GH) stimulation. IGF-1 mediates many of the actions of GH, stimulating the growth of bones and other tissues and promoting the production of lean muscle mass. IGF-1 is a useful indicator of average GH levels. The IGF-1 test is therefore often used to help evaluate for GH deficiency or GH excess. IGF-1 deficiencies are seen early in life and are usually the result of GH deficiency. They can inhibit bone growth and overall development and can result in a child with a shorter than normal stature. In adults, decreased production can lead to low bone density, less muscle mass, and altered lipid levels. Insulin-like growth factor 1 (IGF-1) is an evolutionary conserved peptide, which has been shown to be essential in the regulation of body size, the pattern of reproductive investment and life span across a broad taxonomic range of model species in laboratory and domesticated conditions. However, studies addressing corresponding evolutionary hypotheses on a broader scale and in free-living vertebrates are very rare. This is a very useful research tool to monitor muscle development and metabolism in birds.
Format: Liquid
Storage buffer: Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal
Shipping conditions: Dry ice

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