Anti-IGF

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-IGF
• Research fields: Cell biology;Immunology
• Class: Polyclonal
• Conjugation: Unconjugated
• Molecular weight: 17
• Reactivity: Avian
• Host: Rabbit
• Application: ELISA
• Description: Insulin-like growth factor 1 (IGF-1) is produced by the liver and skeletal muscle as well as many other tissues in response to growth hormone (GH) stimulation. IGF-1 mediates many of the actions of GH, stimulating the growth of bones and other tissues and promoting the production of lean muscle mass. IGF-1 is a useful indicator of average GH levels. The IGF-1 test is therefore often used to help evaluate for GH deficiency or GH excess. IGF-1 deficiencies are seen early in life and are usually the result of GH deficiency. They can inhibit bone growth and overall development and can result in a child with a shorter than normal stature. In adults, decreased production can lead to low bone density, less muscle mass, and altered lipid levels. Insulin-like growth factor 1 (IGF-1) is an evolutionary conserved peptide, which has been shown to be essential in the regulation of body size, the pattern of reproductive investment and life span across a broad taxonomic range of model species in laboratory and domesticated conditions. However, studies addressing corresponding evolutionary hypotheses on a broader scale and in free-living vertebrates are very rare. This is a very useful research tool to monitor muscle development and metabolism in birds.
• Immunogen: Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved in all bird species
• Recommended controls: ELISA: peptide immunogen

Target Details

• Target: Insulin-like growth factor 1 (IGF)
• Molecular weight: 17
• Target background: Insulin-like growth factor 1 (IGF-1) is produced by the liver and skeletal muscle as well as many other tissues in response to growth hormone (GH) stimulation. IGF-1 mediates many of the actions of GH, stimulating the growth of bones and other tissues and promoting the production of lean muscle mass. IGF-1 is a useful indicator of average GH levels. The IGF-1 test is therefore often used to help evaluate for GH deficiency or GH excess. IGF-1 deficiencies are seen early in life and are usually the result of GH deficiency. They can inhibit bone growth and overall development and can result in a child with a shorter than normal stature. In adults, decreased production can lead to low bone density, less muscle mass, and altered lipid levels. Insulin-like growth factor 1 (IGF-1) is an evolutionary conserved peptide, which has been shown to be essential in the regulation of body size, the pattern of reproductive investment and life span across a broad taxonomic range of model species in laboratory and domesticated conditions. However, studies addressing corresponding evolutionary hypotheses on a broader scale and in free-living vertebrates are very rare. This is a very useful research tool to monitor muscle development and metabolism in birds.

Applications

• Application: ELISA

Handling

• Format: Liquid
• Unit size: 100 ug
• Storage buffer: Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal
• Shipping conditions: Dry ice