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#153417

Anti-HA (H1N1) [LM41]

Cat. #153417

Anti-HA (H1N1) [LM41]

Cat. #: 153417

Unit size: 100 ug

Availability: 10-12 weeks

Target: A/WSN (H1N1) hemagglutinin

Class: Monoclonal

Application: ELISA ; Fn

Reactivity: Virus

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Nigel Dimmock

Institute: University of Warwick

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-HA (H1N1) [LM41]
  • Alternate name: Hemagglutinin Antibody, Anti-HA, HA, Antibody, Anti-Influenza A, Anti-H1N1 HA, Influenza A Antibody, Flu Antibody, AWSN Antibody, H1N1 Antibody, Anti-AWSN, A/WSN Antibody, Anti-A/WSN
  • Research fields: Immunology;Microbiology
  • Clone: LM41
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Virus
  • Host: Mouse
  • Application: ELISA ; Fn
  • Description: The hemagglutinin (HA) protein is one of two major surface glycoproteins on the envelope of influenza A virus. The HA protein is responsible for receptor binding to host cells and for viral entry and is therefore the primary target of neutralizing antibodies. LM41 recognises an epitope of the A/WSN (H1N1) HA antigen only when expressed in H-2k cells. LM41 inhibited Ag-specific, MHC class I-restricted lysis of H-2k target cells infected with a vaccinia recombinant virus expressing the HA of A/WSN by CTL from A/WSN virus-infected H-2k mice.
  • Immunogen: C3WHe-mg (H-2k) mice were infected with A/WSN (H1N1)
  • Isotype: IgM
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: A/WSN (H1N1) hemagglutinin
  • Target background: The hemagglutinin (HA) protein is one of two major surface glycoproteins on the envelope of influenza A virus. The HA protein is responsible for receptor binding to host cells and for viral entry and is therefore the primary target of neutralizing antibodies. LM41 recognises an epitope of the A/WSN (H1N1) HA antigen only when expressed in H-2k cells. LM41 inhibited Ag-specific, MHC class I-restricted lysis of H-2k target cells infected with a vaccinia recombinant virus expressing the HA of A/WSN by CTL from A/WSN virus-infected H-2k mice.

Applications

  • Application: ELISA ; Fn

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Dry ice

References

  • McLain et al. 1993. J Immunol. 150(8 Pt 1):3421-6. PMID: 7682240.

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