Cat. #153633
Anti-Estrogen Receptor Beta5 [PPG5/25]
Cat. #: 153633
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Estrogen Receptor ? 5
Class: Monoclonal
Application: IHC ; IF ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: BioServ UK Ltd
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Estrogen Receptor Beta5 [PPG5/25]
- Alternate name: Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2
- Cancer: Breast cancer;Gynaecologic cancer
- Cancers detailed: Breast cancer;Broadly Applicable;Ovarian
- Research fields: Cancer;Immunology;Neurobiology
- Clone: PPG5/25
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IHC ; IF ; WB
- Description: Estrogen receptors are commonly over-expressed in cancers. Clone PPG5/25 recognizes Estrogen Receptor Beta (ERÄÂ?) 5 and is useful in determining the expression of ERÄÂ?5 in cancer cells, mainly via immunohistochemistry.
- Immunogen: Tuberculin conjugated peptide that recognizes C terminus of ER?5 at sequence LLSHVRHARYAP
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
- Recommended controls: Normal colon or colon carcinoma
Target Details
- Target: Estrogen Receptor ? 5
- Tissue cell line specificity: Normal colon or colon carcinoma
- Target background: Estrogen receptors are commonly over-expressed in cancers. Clone PPG5/25 recognizes Estrogen Receptor Beta (ER?) 5 and is useful in determining the expression of ER?5 in cancer cells, mainly via immunohistochemistry.
Applications
- Application: IHC ; IF ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Storage conditions: -80° C
- Shipping conditions: Dry ice
References
- Zannoni et al. 2016. Histopathology. 68(4):541-8. PMID: 26132417.
- Li et al. 2015. Oncol Lett. 10(4):2341-2346. PMID: 26622848.
- Sexual dimorphism in medulloblastoma features.
- Cytoplasm estrogen receptor ?5 as an improved prognostic factor in thymoma and thymic carcinoma progression.
- Gender effect in experimental models of human medulloblastoma: does the estrogen receptor ? signaling play a role?
- Ciucci et al. 2014. PLoS One. 9(7):e101623. PMID: 25000562.
- Collins et al. 2009. BMC Cancer. 9:330. PMID: 19758455.
- Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha.
- Wong et al. 2005. J Pathol. 207(1):53-60. PMID: 15954165.
- ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates.
