Cat. #152936
Anti-DMC1 [5B10/2]
Cat. #: 152936
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: hDMC1. Human equivalent of E.Coli recA
Class: Monoclonal
Application: IHC ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Stephen West
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-DMC1 [5B10/2]
- Alternate name: Disrupted meiotic cDNA 1 homolog, Disrupted meiotic cDNA 1, yeast homolog of, dJ199H16.1, DMC 1, DMC1, DMC1 dosage suppressor of mck1 homolog, DMC1 dosage suppressor of mck1 homolog meiosis specific homologous recombination (yeast), DMC1 homologue
- Research fields: Genetics
- Clone: 5B10/2
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: IHC ; IP ; WB
- Description: May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
- Immunogen: Recombinant fusion protein (Human). DMC1 protein (expressed as 6xHis fusion in E. coli and band cut out of gel of insoluble pellet).
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: hDMC1. Human equivalent of E.Coli recA
- Target background: May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
Applications
- Application: IHC ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Masson et al. 1999. EMBO J. 18(22):6552-60. PMID: 10562567.
- The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51.
