Implicated in hepatocellular carcinoma. CYP8B1 is upregulated in primary and metaststic colorectal tumours compared to normal colon mucosa.
| Inventor | Institute |
|---|---|
| Ayham Alnabulsi | Vertebrate Antibodies Limited |
| Cat. #: | 152155 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology |
| Application: | ELISA ; IHC ; WB |
| Target: | Cytochrome P450, family 8, subfamily B, polypeptide 1 (CYP8B1) |
| Reactivity: | Human ; Rat |
| Clone: | M15-P3B7 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | Implicated in hepatocellular carcinoma. CYP8B1 is upregulated in primary and metaststic colorectal tumours compared to normal colon mucosa. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Immunogen: | Peptide sequence QPSHDVRFR (amino acids 486 494) |
| Myeloma used: | P3X63Ag8.653 |
| Target background: | Implicated in hepatocellular carcinoma. CYP8B1 is upregulated in primary and metaststic colorectal tumours compared to normal colon mucosa. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer. Swan et al. 2016. Oncotarget. :. PMID: 27341022. |
|---|
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