X121.1 may be used to immunoprecipitate active CDK1 complexes.
| Inventor | Institute |
|---|---|
| Julian Gannon | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| Cat. #: | 151181 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Genetics |
| Application: | WB ; IHC ; IP ; WB |
| Target: | Cyclin B2 |
| Reactivity: | Xenopus laevis |
| Clone: | X121.10 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Cyclin B2; HsT17299 |
|---|---|
| Product description: | X121.1 may be used to immunoprecipitate active CDK1 complexes. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | Xenopus laevis Cyclin B2 |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs). |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.91 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Integrative module analysis of HCC gene expression landscapes Li et al. 2020. Exp Ther Med. 19(3):1779-1788. PMID: 32104233. Identification of the nuclear localization signal in Xenopus cyclin E and analysis of its role in replication and mitosis. Activation of Xenopus eggs by the kinase inhibitor 6-DMAP suggests a differential regulation of cyclin B and p39(mos) proteolysis. |
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