Cat. #151020
Anti-CyclinB1 [V143.1]
Cat. #: 151020
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Cyclin B1
Class: Monoclonal
Application: WB
Reactivity: Mouse
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Julian Gannon
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CyclinB1 [V143.1]
- Alternate name: CCNB1; Cyclin B1; G2/Mitotic-Specific Cyclin B1; CCNB
- Research fields: Cancer;Cell biology;Genetics
- Clone: V143.1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Mouse
- Host: Mouse
- Application: WB
- Description: V143.1 is exceptionally good at detecting Cyclin B1 in western blots, giving a very strong signal with minimal background.
- Immunogen: His tagged cyclin B1 (hamster) expressed in bacteria.
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Cyclin B1
- Target background: Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs). Cyclin B1 is a marker of cell proliferation and a key component of the cell cycle progression machinery. Cyclin B1 may prove to be a prognostic marker in neoplasia.
Applications
- Application: WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: '-15° C to -25° C
- Shipping conditions: Dry ice
References
- Shen et al. 2010. Cell Cycle. 9(23):4720-34. PMID: 21099356.
- Female infertility in PDE3A(-/-) mice: polo-like kinase 1 (Plk1) may be a target of protein kinase A (PKA) and involved in meiotic arrest of oocytes from PDE3A(-/-) mice.
