Anti-CLEC9A [7H11]

Recognises mouse DNGR-1, also known as CLEC9A, which is a highly specific marker of the CD8a+ and the CD103+ DC subsets, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.

Contributors

Institute
Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Cat. #: 151706
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Immunology;Stem cell biology
Application: ELISA ; FACS ; IF ; IP ; WB
Target: Mouse DNGR1
Reactivity: Mouse
Clone: 7H11
Host: Rat
Class: Monoclonal
Alternate name: C-Type Lectin Domain Family 9 Member A; HEEE9341; UNQ9341; DNGR-1; CD37; DNGR1
Product description: Recognises mouse DNGR-1, also known as CLEC9A, which is a highly specific marker of the CD8a+ and the CD103+ DC subsets, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.
Conjugation: Unconjugated
Isotype: IgG1
Immunogen: RBL-2H3 cells expressing mouse DNGR-1 fused to an HA epitope
Myeloma used: Y3.AG.1.2.3
Target background: Recognises mouse DNGR-1, also known as CLEC9A, which is a highly specific marker of the CD8a+ and the CD103+ DC subsets, as well as a receptor able to recognise a preformed signal exposed on necrotic cells.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Joffre et al. 2010. Eur J Immunol. 40:1255-65. [PMID: 20333625]

Sancho et al. 2008. J Clin Invest 118:2098-110 .[PMID: 18497879]

Sancho et al. 2009. Nature. 458:899-903. [PMID: 19219027]

Li et al. 2015. Eur J Immunol. 45(3):854-64. PMID: 25487143.

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