Cat. #151190
Anti-Cdc6 [cdc6 9H8/5]
Cat. #: 151190
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Cell-division cycle protein 6 (cdc6)
Class: Monoclonal
Application: IHC ; IP ; WB
Reactivity: Saccharomyces cerevisiae
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Cdc6 [cdc6 9H8/5]
- Alternate name: Cell Division Cycle 6; Cdc18-Related Protein; CDC6-Related Protein; P62(Cdc6); HsCDC18; CDC18L; HsCDC6; CDC6 Cell Division Cycle 6 Homolog
- Research fields: Cell biology;Genetics
- Clone: cdc6 9H8/5
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Saccharomyces cerevisiae
- Host: Mouse
- Application: IHC ; IP ; WB
- Description: Cdc6 is essential for assembling the pre-replicative complex that forms at origins of DNA replication in the G1 phase of the cell cycle in budding yeast (S. cerevisiae).
- Immunogen: cdc6 from S.Cerevisiae.
- Isotype: IgG1
Target Details
- Target: Cell-division cycle protein 6 (cdc6)
- Target background: Cdc6 is essential for assembling the pre-replicative complex that forms at origins of DNA replication in the G1 phase of the cell cycle in budding yeast (S. cerevisiae).
Applications
- Application: IHC ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Evrin et al. 2013. Nucleic Acids Res. 41(5):3162-72. PMID: 23376927.
- A yeast GSK-3 kinase Mck1 promotes Cdc6 degradation to inhibit DNA re-replication.
- Ikui et al. 2012. PLoS Genet. 8(12):e1003099. PMID: 23236290.
- Zhang et al. 2007. Cancer Res. 67(8):3827-34. PMID: 17440097.
- Tumor necrosis factor receptor 1/c-Jun-NH2-kinase signaling promotes human neoplasia.
- Perkins et al. 2001. EMBO J. 20(17):4836-45. PMID: 11532947.
- Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis.
- Donovan et al. 1997. Proc Natl Acad Sci U S A. 94(11):5611-6. PMID: 9159120.
- Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast.
