Cat. #151436

Anti-CD70 [BU69] mAb

Name: Anti-CD70 [BU69] mAb
SKU: 151436
Availability: InStock

Cat. #: 151436

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: CD70

Class: Monoclonal

Application: FACS ; IHC ; IP

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

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Contributor

Inventor: Roy Jefferis

Institute: University of Birmingham

Tool Details

Target Details

Applications

Handling

References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

Name: Anti-CD70 [BU69] mAb
Alternate name: CD7 Molecule; Tumor Necrosis Factor Ligand Superfamily Member 7; CD27 Ligand; CD27LG; TNFSF7; CD27L; Tumor Necrosis Factor Ligand 8A; Surface Antigen CD7; Ki-24 Antigen; CD7 Antigen; TNLG8A
Research fields: Apoptosis and autophagy;Cancer;Immunology;Stem cell biology
Clone: BU69
Tool sub type: Primary antibody
Class: Monoclonal
Conjugation: Unconjugated
Molecular weight: 30 kDa
Strain: Balb/c
Reactivity: Human
Host: Mouse
Application: FACS ; IHC ; IP
Description: BU69 inhibits T cell proliferation induced by dendritic cells.
Immunogen: Waldenstroms macroglobulineamia cell line WM-1
Isotype: IgG1
Myeloma used: P3/NS1/1-Ag4.1
Recommended controls: Raji cells

Target Details

Target: CD70
Molecular weight: 30 kDa
Tissue cell line specificity: Raji cells
Target background: CD70 is a 30kDa ligand of the receptor CD27. Both belong to the tumour necrosis factor receptor superfamily 7. Receptor activation can induce proliferation and apoptosis.

Applications

Application: FACS ; IHC ; IP

Handling

Format: Liquid
Concentration: 1 mg/ml
Unit size: 100 ug
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice

References

Schlossman, S.F. et al. 1995 Leukocyte Typing V Oxford University Press
Ito et al. 1999. J Immunol. 163(3):1409-19. PMID: 10415041.
A CD1a+/CD11c+ subset of human blood dendritic cells is a direct precursor of Langerhans cells.