Cat. #160510
Anti-CD54 [YN1/1.7.4]
Cat. #: 160510
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: CD54
Class: Monoclonal
Application: IP ; FACS ; WB
Reactivity: Mouse
Host: Rat
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Fumio Takei
Institute: BC Cancer
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD54 [YN1/1.7.4]
- Alternate name: ICAM-1
- Research fields: Cancer;Immunology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 95 kDa
- Reactivity: Mouse
- Host: Rat
- Application: IP ; FACS ; WB
- Description: CD-54, also known as ICAM-1, is a cell surface glycoprotein expressed on epithelial, lymphocytes, macrophages, dendritic cells, and other immune cells. It plays a role in cellular signalling to stabilize cell-cell interactions and also binds to integrins of type CD11a/CD18 and CD11b/CD18. It has also been shown to be a target for rhinoviruses. This antibody recognizes the murine lymphocyte antigen MALA-2. This antibody inhibits the mixed lymphocyte response and inhibits Con A blasts to MALA-2.This antibody was purified from ascite fluid using ammonium sulfate (50% saturation) precipitation followed by DEAE affi-gel blue chromatography.
- Immunogen: NS-1 cells
- Isotype: IgG2b kappa
- Myeloma used: Y3
Target Details
- Target: CD54
- Molecular weight: 95 kDa
- Target background: CD-54, also known as ICAM-1, is a cell surface glycoprotein expressed on epithelial, lymphocytes, macrophages, dendritic cells, and other immune cells. It plays a role in cellular signalling to stabilize cell-cell interactions and also binds to integrins of type CD11a/CD18 and CD11b/CD18. It has also been shown to be a target for rhinoviruses. This antibody recognizes the murine lymphocyte antigen MALA-2. This antibody inhibits the mixed lymphocyte response and inhibits Con A blasts to MALA-2.This antibody was purified from ascite fluid using ammonium sulfate (50% saturation) precipitation followed by DEAE affi-gel blue chromatography.
Applications
- Application: IP ; FACS ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Dry ice
References
- Horley et al. 1989. EMBO J. 8(10):2889-96. PMID: 2573511.
- Takei et al. 1985. J Immunol. 134(3):1403-7. PMID: 2981916.
