UCH-M1 can be used to investigate specific in vitro antibody responses to influenza virus by human lymphocytes.
| Inventor | Institute |
|---|---|
| Peter Beverley | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151174 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Immunology;Stem cell biology;Tissue-specific biology |
| Application: | FACS ; IHC ; IF |
| Target: | CD14 |
| Reactivity: | Human |
| Clone: | UCH-M1 |
| Host: | Mouse |
| Class: | Monoclonal |
| Primary citation: | Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324. |
| Alternate name: | CD14 Molecule; CD14 Antigen; Myeloid Cell-Specific Leucine-Rich Glycoprotein |
|---|---|
| Product description: | UCH-M1 can be used to investigate specific in vitro antibody responses to influenza virus by human lymphocytes. |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Molecular weight: | 52 kDa |
| Immunogen: | Thymocytes and peripheral blood leucocytes (PBL) |
| Immunogen Uniprot ID: | P08575 |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | CD14 is found in human monocytes and vascular endothelium in some tissues. CD14 binds the endotoxin lipopolysaccharide. |
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| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Sadeghi et al. 2016. PLoS One. 11(10):e0162667. PMID: 27695085. GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes. Goya et al. 2006. Prostate. 66(15):1573-84. PMID: 16927388. Prostate-specific antigen induces apoptosis of osteoclast precursors: potential role in osteoblastic bone metastases of prostate cancer. Puig-Krger et al. 2004. J Biol Chem. 279(24):25680-8. PMID: 15070901. Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages. Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324. Monoclonal antibodies specific for human monocytes, granulocytes and endothelium. Mitchell et al. 1983. Immunology. 50(2):239-50. PMID: 6578194. Accessory cell and HLA compatibility requirements for the generation of specific in-vitro antibody responses to influenza virus by human blood lymphocytes. |
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