Cat. #151791
Anti-CD11C [CD11C-100/D2]
Cat. #: 151791
Unit size: 100 ug
Availability: 10-12 weeks
Target: CD11C, Integrin, alpha X (complement component 3 receptor 4 subunit). ITGAX
Class: Monoclonal
Application: IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Jacqueline Cordell
Institute: University of Oxford
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD11C [CD11C-100/D2]
- Alternate name: Integrin Subunit Alpha X; Leukocyte Adhesion Glycoprotein P15;95 Alpha Chain; Complement Component 3 Receptor 4 Subunit; Leukocyte Adhesion Receptor P15;95; CD11 Antigen-Like Family Member C; CD11C
- Research fields: Cell biology;Cell signaling and signal transduction;Immunology;Stem cell biology
- Clone: CD11C-100/D2
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IP ; WB
- Description: The integrin alpha X chain protein (CD11c) belongs to the ?ĂÂ2 integrin subfamily. Integrins are cell surface receptors composed of a heterodimer containing an a and ?ĂÂ subunit. CD11c (the a subunit) combines with CD18 (the ?ĂÂ subunit) to form the leukocyte specific integrin inactivated-C3b receptor 41,2. CD11c is known to be expressed on monocytes/macrophages, granulocytes, activated B cells, in spleen and in bone marrow.
- Immunogen: Synthetic peptide conjugated to KLH corresponding to the C terminus of human CD11C: ANGQIAPENGTQTPSPPSEK
- Isotype: IgG2a
- Myeloma used: NS0
- Recommended controls: Human tonsil
Target Details
- Target: CD11C, Integrin, alpha X (complement component 3 receptor 4 subunit). ITGAX
- Target background: The integrin alpha X chain protein (CD11c) belongs to the ?ĂÂ2 integrin subfamily. Integrins are cell surface receptors composed of a heterodimer containing an a and ?ĂÂ subunit. CD11c (the a subunit) combines with CD18 (the ?ĂÂ subunit) to form the leukocyte specific integrin inactivated-C3b receptor 41,2. CD11c is known to be expressed on monocytes/macrophages, granulocytes, activated B cells, in spleen and in bone marrow.
Applications
- Application: IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Unit size: 100 ug
- Storage buffer: RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Myones BL, et al., J Clin Invest. 1988 (2):640-51. PMID: 2969921 Bilsland et al., 1994. J. Immunol. 152(9):4582-9. PMID: 7512600 Ihanus E, et al., Blood. 2007 109(2):802-10. PMID: 16985175 Ammon C et al. Immunology. 2000. 100(3):364-9. PMID: 10929059
