#154129

Anti-Big (high-molecular-weight) tau

Cat. #154129

Anti-Big (high-molecular-weight) tau

Cat. #: 154129

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: Big tau (high-molecular-weight)

Class: Polyclonal

Application: IHC ; WB

Reactivity: Rat

Host: Rabbit

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Itzhak Fischer

Institute: Drexel University

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Big (high-molecular-weight) tau
  • Research fields: Developmental biology;Neurobiology
  • Tool sub type: Primary antibody
  • Class: Polyclonal
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Reactivity: Rat
  • Host: Rabbit
  • Application: IHC ; WB
  • Description: Tau is a neuronal microtubule associated protein (MAP) which has multiple isoforms that are differentially expressed during development. Big tau is a high molecular weight isoform that contains an additional large exon (4a) and is expressed primarily by neurons in the peripheral nervous system. Big tau expression has also been shown in the developing spinal cord and in the adult central nervous system. Big tau may be important in stabilizing microtubules in axons that are subjected to great s...
  • Immunogen: Recombinant protein of the complete 4a exon of tau, specific to the Big tau isoform, was used to produce antibody

Target Details

  • Target: Big tau (high-molecular-weight)
  • Tissue cell line specificity: Rabbit
  • Target background: Tau is a neuronal microtubule associated protein (MAP) which has multiple isoforms that are differentially expressed during development. Big tau is a high molecular weight isoform that contains an additional large exon (4a) and is expressed primarily by neurons in the peripheral nervous system. Big tau expression has also been shown in the developing spinal cord and in the adult central nervous system. Big tau may be important in stabilizing microtubules in axons that are subjected to great s...

Applications

  • Application: IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Boyne et al. 1995. J Comp Neurol. 358(2):279-93. PMID: 7560287.
  • Distribution of Big tau in the central nervous system of the adult and developing rat.