Cat. #155090
Anti-AvW-1 (von Willebrand Factor) [A8-1]
Cat. #: 155090
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: von Willebrand Factor
Class: Monoclonal
Application: ELISA ; IF ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Versiti Blood Research Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-AvW-1 (von Willebrand Factor) [A8-1]
- Alternate name: vWf
- Research fields: Immunology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Molecular weight: 250 kDa
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IF ; IP ; WB
- Description: von Willebrand factor (vWF) is a multimeric glycoprotein that functions in hemostasis as the initiator of platelet adhesion at the site of vascular injury and as the carrier of the anti-hemophilic factor, factor VIII (FVIII). Hereditary or acquired defects of VWF lead to von Willebrand disease (vWD), a bleeding diathesis of the skin and mucous membranes, causing nosebleeds, menorrhagia, and gastrointestinal bleeding.
- Immunogen: vWF (COOH terminus of mature vWF)
- Myeloma used: P3X63Ag8.653
- Recommended controls: IgG2a
Target Details
- Target: von Willebrand Factor
- Molecular weight: 250 kDa
- Tissue cell line specificity: Mouse
- Target background: von Willebrand factor (vWF) is a multimeric glycoprotein that functions in hemostasis as the initiator of platelet adhesion at the site of vascular injury and as the carrier of the anti-hemophilic factor, factor VIII (FVIII). Hereditary or acquired defects of VWF lead to von Willebrand disease (vWD), a bleeding diathesis of the skin and mucous membranes, causing nosebleeds, menorrhagia, and gastrointestinal bleeding.
Applications
- Application: ELISA ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Flood et al. 2018. Res Pract Thromb Haemost. 2(2):390-398. PMID: 30046743.
- Haberichter et al. 2008. Blood. 111(10):4979-85. PMID: 18344424.
- Rosenberg et al. 2002. Blood. 100(5):1699-706. PMID: 12176890.
- Hillery et al. 1998. Blood. 91(5):1572-81. PMID: 9473222.
- Rosenberg et al. 1998. J Clin Invest. 101(3):613-24. PMID: 9449695.
- Scott et al. 1991. Am J Clin Pathol. 96(6):723-8. PMID: 1746488.
- Kroner et al. 1991. J Biol Chem. 266(29):19146-9. PMID: 1918030.
- Montgomery et al. 1986. ...
