Cat. #155098
Anti-AP-1 (Glycoprotein Ib) [MBC-1]
Cat. #: 155098
Unit size: 100 ug
Target: Glycoprotein 1B
Class: Monoclonal
Application: ELISA
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Versiti Blood Research Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-AP-1 (Glycoprotein Ib) [MBC-1]
- Alternate name: GpIb
- Research fields: Immunology
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 145
- Reactivity: Human
- Host: Mouse
- Application: ELISA
- Description: GPIb is a platelet glycoprotein and a receptor for von Willebrand factor. Consists of alpha and beta subunits. Forms a multiprotein complex with GPIX and GPV. Binding of VWF to this complex initiates platelet adhesion to the sub-endothelium after vascular injury. Binding of AP-1 to GP1b alpha inhibits binding of VWF to GP1b alpha.
- Immunogen: GPIba
- Myeloma used: P3X63Ag8.653
- Recommended controls: IgG1
Target Details
- Target: Glycoprotein 1B
- Molecular weight: 145
- Target background: GPIb is a platelet glycoprotein and a receptor for von Willebrand factor. Consists of alpha and beta subunits. Forms a multiprotein complex with GPIX and GPV. Binding of VWF to this complex initiates platelet adhesion to the sub-endothelium after vascular injury. Binding of AP-1 to GP1b alpha inhibits binding of VWF to GP1b alpha.
Applications
- Application: ELISA
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Rosenberg et al. 2002. Blood. 100(5):1699-706. PMID: 12176890.
- Sims et al. 1991. J Biol Chem. 266(12):7345-52. PMID: 1902217.
- Okita et al. 1985. J Cell Biol. 100(1):317-21. PMID: 3155520.
