#153274

Anti-5-Hydroxymethylcytosine (5hmc) [AB3/63.3] rAb

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Cat. #153274

Anti-5-Hydroxymethylcytosine (5hmc) [AB3/63.3] rAb

Cat. #: 153274

Sub-type: Primary antibody

Unit size: 100 ug

Target: 5-Hydroxymethylcytosine (5hmC)

Class: Recombinant

Application: IF ; IP ; DB

Reactivity: All

Host: Rat

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Contributor

Inventor: Wolf Reik

Institute: Absolute Antibody ; Babraham Institute

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-5-Hydroxymethylcytosine (5hmc) [AB3/63.3] rAb
  • Research fields: Genetics
  • Clone: AB3/63.3
  • Tool sub type: Primary antibody
  • Class: Recombinant
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Reactivity: All
  • Host: Rat
  • Application: IF ; IP ; DB
  • Description: The anti-5-Hydroxymethylcytosine antibody, clone AB3/63.3, detects 5-hydroxymethyl cytosine (hmc, 5hmc), but not 5-methylcytosine or unmethylated cytosine. 5-Hydroxymethylcytosine is a DNA pyrimidine nitrogen base. It is formed from the DNA base cytosine by adding a methyl group and then a hydroxy group. Every mammalian cell contains 5-hydroxymethylcytosine, but the levels vary depending on the cell type; generally, the levels of 5-hydroxymethylcytosine increase with age. Although the exact...
  • Immunogen: 5-Hydroxymethylcytosine conjugated to BSA
  • Isotype: IgG2a kappa
  • Recommended controls: Unmodified DNA, 5-Methylcytosine DNA, and 5-hydroxymethylcytosine DNA

Target Details

  • Target: 5-Hydroxymethylcytosine (5hmC)
  • Tissue cell line specificity: Mouse
  • Target background: The anti-5-Hydroxymethylcytosine antibody, clone AB3/63.3, detects 5-hydroxymethyl cytosine (hmc, 5hmc), but not 5-methylcytosine or unmethylated cytosine. 5-Hydroxymethylcytosine is a DNA pyrimidine nitrogen base. It is formed from the DNA base cytosine by adding a methyl group and then a hydroxy group. Every mammalian cell contains 5-hydroxymethylcytosine, but the levels vary depending on the cell type; generally, the levels of 5-hydroxymethylcytosine increase with age. Although the exact...

Applications

  • Application: IF ; IP ; DB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

References

  • Original hybridoma first published in: Wossidlo et al. 2011. Nat Commun. 2:241. PMID: 21407207.