Cat. #158364
MZ1 small molecule (tool compound)
Cat. #: 158364
Availability: Please enquire for quantities and pricing
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Alessio Ciulli ; Michael Zengerle ; Kwok-Ho Chan
Institute: University of Dundee
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Tool name: MZ1 small molecule (tool compound)
- Alternate name: BRD4, CAP, bromodomain containing 4, chromosome-associated protein, HUNK1, HUNKI, MCAP
- Research fields: Genetics
- Molecular formula: C49H60ClN9O8S2
- Primary target: BRD4
- Description: (+)-JQ1 based PROTAC that selectively degrades BRD4 in cells
- Molecular weight: 1002.64
- Solubility: DMSO; Ethanol
Handling
- Purity: 1002.64 g/mol
- Shipping conditions: Dry Ice
Target Details
- Primary target: BRD4
References
- Zengerle et al. 2015. ACS Chem Biol. 10(8):1770-7. PMID: 26035625.