Cat. #153191

CDK inhibitor BS-194 Small Molecule (Tool Compound)

Cat. #: 153191

Sub-type: Inhibitor

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Contributor

Inventor: Simak Ali

Institute: Imperial College London

Tool Details

Handling

Target Details

Related Tools

References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

Tool name: CDK inhibitor BS-194 Small Molecule (Tool Compound)
Research fields: Cancer;Genetics
Molecular formula: C20H27N5O3
Tool sub type: Inhibitor
Description: BS-194 is a selective and potent CDK inhibitor, which inhibits CDK2, CDK1, CDK5, CDK7, and CDK9.
Purpose: Inhibitor
Selectivity: CDK1, CDK2, CDK7, and CDK9
Iupac: (2S,3S)-3-(7-(benzylamino)-3- isopropylpyrazolo[1,5-a]pyrimidin-5- ylamino)butane-1,2,4-triol
Molecular weight: 385.5

Handling

Purity: 385.5 g/mol
Storage conditions: Ambient
Shipping conditions: Dry Ice

Target Details

Ic50: CDK2, CDK1, CDK5, CDK7, and CDK9 (IC50=3, 30, 30, 250, and 90 nmol/L, respectively)

Related Tools

Related tools: CDK7 inhibitor BS-181 Small Molecule (Tool Compound)

References

J. Med. Chem. 2010, 53, 85088522