Cat. #157994
anti-glutamate carboxypeptidase (GCPII) iBody small molecule (tool compound)
Cat. #: 157994
Sub-type: Marker
Availability: Please enquire for quantities and pricing
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Jan Konvalinka ; Jirí Schimer ; Tomas Knedlik ; Jan Tykvart ; Frantisek Sedlak ; Pavel Majer ; Vaclav Navratil ; Petr Cigler ; Vladimir Subr ; Karel Ulbich ; Jiri Stroham ; Pavel Sacha
Institute: Institute of Organic Chemistry and Biochemistry ; Institute of Macromolecular Chemistry ; Charles University
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Tool name: anti-glutamate carboxypeptidase (GCPII) iBody small molecule (tool compound)
- Alternate name: Glutamate Carboxypeptidase II, N-acetyl-L-aspartyl-L-glutamate peptidase I (NAALADase I), NAAG peptidase, prostate-specific membrane antigen (PSMA)
- Research fields: Cell signaling and signal transduction;Other
- Tool sub type: Marker
- Primary target: Targeting human Glutamate Carboxypeptidase II (GPCII) using GPCII specific inhibitor
- Description: An enzyme that in humans is encoded by FOLH1 (folate hydrolase 1). - iBodiesŽ are capable of replacing antibodies in biomedical applications such as ELISA, flow cytometry, confocal microscopy, immunocytochemistry, Western Blot and immunoprecipitation. - These iBodiesŽ consist of an N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer decorated with low-molecular-weight compounds that function as targeting ligand (e.g., enzyme inhibitors, receptor ligands), affinity anchor (e.g., biotin) and/o...
- Purpose: Marker
- Additional notes: HPMA conjugate characteristics: MW: 148 800g/mol #Biotins/molecule: 38 Fluorochrome name: ATTO488 #Fluorochrome/molecule: 7 iBodies(R) is a registered trade mark of IOCB Tech s.r.o.
Handling
- Shipping conditions: Dry Ice
Target Details
- Primary target: Targeting human Glutamate Carboxypeptidase II (GPCII) using GPCII specific inhibitor
Related Tools
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References
- Ĺ imon et al. 2018. ACS Chem Biol. 13(12):3333-3342. PMID: 30489064.
- DvoĹĂĄkovĂĄ et al. 2017. J Med Chem. 60(20):8385-8393. PMID: 28953383.
- Ĺ ĂĄcha et al. 2016. Angew Chem Int Ed Engl. 55(7):2356-60. PMID: 26749427.
