Anti-SV40T [Pab 430] Product
SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins.
CDK2 inhibitor NU6301 Small Molecule (Tool Compound) Product
[…] inhibit cell growth by 50%) 14 ÎźM versus >30 ÎźM), and was more growth-inhibitory in p53 mutant or null versus p53 WT cells (p=0.02), and in Rb (retinoblastoma protein) WT […]
Anti-ASPP1 [ASPP1] Product
iASPP1 inhibits the proaptotic functions of ASPP1 and p53.
Anti-pTpY Cdk1 [CP3.2] Product
[…] associates with cyclin A at the end of S phase and targets proteins such as p53, BARD1, and BRCA2 involved in cell cycle progression, and others involved in DNA replication. […]
HCT 116 p300 KO [D10] Cell Line Product
HCT 116 p300 KO Cell Line is a tool for the in vitro study of p300 in colon carcinoma, and specifically of its role in p53-dependent apoptosis, cellular, adhesion and migration
Anti-SV40ST [pab 280] Product
SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins.
Anti-SV40LT [LP7N] Product
SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins.
Anti-TIGAR [9C10] Product
TIGAR (TP53 induced glycolysis and apoptosis regulator) is a novel p53-inducible gene, that shows similarity to the bisphosphatase domain of the biFn enzyme 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase, the main regulator of glycolysis.
Anti-Plx [AZ44] Product
[…] a mitotic regulator conserved from yeasts to humans. Many key cell cycle regulators such as p53, cdc25, cyclin B and the Anaphase Promoting Complex are directly targeted by Plx.The Anaphase […]
Anti-Plx [AZ34] Product
[…] (Plx) is a mitotic regulator conserved from yeasts to humans. Many key cell cycle regulators such as p53, cdc25, cyclin B and the Anaphase Promoting Complex are directly targeted by Plx.
