Targeting the difficult-to-drug protein – MYC Blog Post

[…] targeting a protein that was, and still is, considered by many to be “difficult-to-drug” – MYC. The MYC protein sits within the nuclei and acts as a ‘master regulator’ of a variety of […]

Anti-cMyc [PM3E7] Product

The c- Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. c-Myc is expressed in proliferating tissues and increased c-Myc […]

Adapted from Mittal et al. 2013. PLoS One. 8(8)

Anti-cMyc [9E11] Product

The c- Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. c-Myc is expressed in proliferating tissues and increased c-Myc […]

Anti-Myc tag [5A5] (ChIP Grade) Product

A myc tag is a polypeptide protein tag derived from the c-myc gene product that can be added to a protein using recombinant DNA technology.

Protein extracts of U87-MG glioblastoma cells with Doxycycline-inducible vectors for Omomyc-RFP and Omomyc were probed with anti-Omomyc 17. Purified antibody is at 7.3 mg/ml.

Anti-Omomyc [21-1-3] Product

Monoclonal antibody specific for Omomyc, capable of suppressing Myc-induced oncogenesis.

Investigating undruggable targets in cancer research Blog Post

[…] targets in cancer are often known oncogenes or tumour suppressors. These include transcription factors such as MYC, MYB, p53, STAT3, nuclear factor-κB (NF-κB), and fusion transcription factors frequently associated with paediatric cancers. The RAS family also belong […]

pCAG_smFP Myc vector Product

CAG driven vector expressing antigenic protein tags, “spaghetti monster� fluorescent proteins (smFPs), with a Myc epitope tag. For mammalian expression.

Anti-cMyc [9E10] Product

Monoclonal antibody raised against sequence of c- Myc, a proto-oncogene heavily implicated in a variety of (hematopoietic) cancers, which has been used in cancer research to detect and understand the […]

K14MycER Mouse Product

In vivo study of Myc activation in skin; in vivo study of skin cell proliferation & differentiation (sebocytes, epidermis)